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[摘要]
从石竹科植物瞿麦 Dianthus superbus L.中分得6种成分,经波谱分析鉴定为:大黄素甲醚(physcion,)、大黄素(emodin,)、3,4-二羟基苯甲酸甲酯(Ⅱ)、3-(3,4′-二羟基苯基)丙酸甲酯()、β-谷甾醇苷()和大黄素-8-O-葡萄糖苷(emodin-8-O-glucoside,)。其中化合物(200μg/kg)对受孕大鼠具有明显抗早孕作用
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[Abstract]
Six compounds were isolated from the aerial parts of Dianthus superbus L..Bycombination of physical constants and spectral analysis,their structures were identified as phycion (Ⅰ),emodin (Ⅱ),methyl 3,4- dihydroxybenzoate (Ⅲ),methyl 3-(3,4-dihydroxyphenyl) propionate (Ⅳ),β-sito-sterol-3- O- glucoside (Ⅴ) and emodin-8- O-glucoside (Ⅵ).All of these constituents were isolated fromthe title plant for the first time.Among them,compoundⅢ showed potent anti-pregnancy activity,given200μ g /kg to pregnant rat can terminate pregnancy at its early stage of pregnancy.
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