从紫花高乌头根的苯提取物中分离到3个二萜生物碱,经理化性质和光谱分析分别鉴定为lappaconitine(I)、ranaconitine(Ⅱ)和 septentriodine(Ⅲ)。化合物 Ⅱ和Ⅲ为首次从该植物中分离到,其中Ⅱ含量最高,根据文献报道Ⅰ和Ⅱ是抗心率失常和镇痛作用的有效成分。

Three diterpenoid alkaloids were obtained from the C_6H_6 extract of the root of Aconitum excelsum. Their structures were identified on the basis of spectral data (MS, IR, ~1HNMR, ~(13)CNMR, DEPT) and physico-chemical properties as lappaconitine (I), ranaconitine (Ⅱ) and septentriodine（Ⅲ). Compounds Ⅱand Ⅲ were obtained for the first time from this plant. Compounds Ⅰ and Ⅱ exhibited analgesic and antiarrhythmic activities, as documented in literature reports.

国家自然科学基金39560087