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[摘要]
用放射免疫法测定了中药鹿茸雌二醇和睾酮的含量。结果显示澳鹿茸雌二醇含量(15.3±1.82)ng/mL,梅花鹿茸的含量为(11.4±1.26) ng/mL与鹿角镑(1.96±0.26) ng/mL相比有极显着性差异(P<0.01),鹿茸伪品和鹿角胶的雌二醇含量与鹿角镑相比没有显着性差异(P>0.05),提示雌二醇是鹿茸治疗宫冷不孕的物质基础;测定鹿茸中雌二醇的含量可作为评价鹿茸品质的依据;鹿茸中睾酮的含量低,提示睾酮不是鹿茸壮阳的有效成分,进一步研究鹿茸中促雄激素样物质,必将为鹿茸的壮阳作用提供依据。
[Key word]
[Abstract]
The Chinese traditional drug, pilose antler was assayed to establish its quality standard. The contents of extradiol and testosterone in pilose antler were determined by radiommunoassay. Their high estradiol levels in pilose antler of Cervus australicum (15.3±1.82) ng/g and of C.nippon (11.40±1.26) ng/g were both highly significant different (P<0.01) as compared with ossified antler (1.90±0.26) ng/g. The counterfeit pilose antler and antler glue contained low levels of estradiol, having no significant differences from ossified antler (P<0.05). And there were no significant differences of testosterone levels in 5 crude drugs mentioned above. An assay of estradiol in pilose antler may correctly evaluate the quality of the crude drug.
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