体外试验中,采用MTT比色法测定当归醇沉物对小鼠脾及胸腺淋巴细胞增殖功能的影响。结果显示,0.16～2.50 ｍg/ｍＬ范围内的当归醇沉物能单独或协同 ConA/LPS发挥促进小鼠脾脏及胸腺Ｔ、Ｂ淋巴细胞增殖的作用。当归醇沉物尚可对抗氢化泼尼松(HP)对ConA诱导的脾脏及胸腺Ｔ淋巴细胞的增殖反应的抑制作用。

Sediment (ESA) obtained from the alcoholic precipitate of extract of tuber of Agelica sinensis (Oliv.)Diels in the preparation of Angelica injection was considered as a waste product. Its effect on lymphocyte proliferation of mice spleen and thymus was tested in vitro by MTT colorimetry. Results showed that at concentrations in the range of 0. 16 ~2. 50 mg/mL. ESA significantly promoted T,B lymphocyte proliferation either alone or with ConA/LPS, and can also antagonize hydroprednisone induced suppression of T lymphocyte proliferation in vitro.

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