采用大鼠足跖肿胀法和紫外可见分光光度法，研究了天然牛黄、胆红素含量不同的培植牛黄以及鸡胆汁对大鼠角叉菜胶性和甲醛性的足跖肿胀率和炎性组织中PGE₂含量的影响。结果表明，天然牛黄，中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE₂含量。经F-检验，这4种中药的作用相互间差异无显著性。

Effects of natural cow-bezoar,cultured cow-bezoar with different bilirubin content and chicken bile on rat paw edema induced by carrageenin and formaldehyde and the postaglandin E₂ (PGE₂) content of inflammatory tissues of rat were determined by foot-digitoplantar turgorneter and UV spectrophotometry. Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde in rat.They also decreased the content of PGE₂ in inflammatory tissues of rats,but results were not statistically significant when treated with F-test.

内蒙古自治区自然科学基金