选择毛细管区带电泳分离模式，以麻黄素为内标建立了适合莨菪类生物碱阿托品、东莨菪碱、山莨菪碱、樟柳碱化化分离与颠茄酊剂及片剂定量分析的高效毛细管电泳方法。电泳分离条件：毛细管40c×50μm，运行缓冲液(pH8.0)50mmol/L磷酸盐溶液-四氢呋喃(9:1)，电迁移进样5kV×5s，运行电压11kV(+)→(-)，柱上检测UV200um，0.02AUFS，毛细管柱温24℃。本法简便、快速、重现性好，可用于含莨菪类生物碱中药制剂的质量控制。

A high performance capillary electrophoresis (HPCE)method was established for the systematic separation of tropane aldaloids , i. e. , atropine , scopolamine , anisodamine and anisodine , and quantitative analysis of Tincture and Tablet Belladonna,based on the mode of capillary zone electrophoresis. A buffer solution composed of 50 mmol/L sodium dihydrogenphosphate at pHB. 0 containing 100o tetrahydrofuran was found to be the most suitable electrolyte for this separation. The electromigration was performed on the 40 cm X 50 pm uncoated capillary with a 11 kV running voltage. The analytes were monitered by on-line ultraviolet (UV)detection at 200 nm and ephedripe was selected as internal standard. The analytical results demonstrated the method was simple,rapid and well reproducible and could be used as a reliable tool for the quality con- trol of Chinese medicines containing tropane alkaloids.