用反相高效液相色谱法测定了川芎单煎剂，川芎、丹参合煎剂，川芎、当归合煎剂及改味四物场中阿魏酸的含量。结果表明，各组汤剂中阿魏酸的含量有显著差异（P＜0．001），配伍熟地对阿魏酸的溶出具有助溶作用。

A simple,rapid,and sensitive reversed phase high performance liquid chromatographic (Rp-HPLC) method for the analysis of ferulic acid(FA) in decoctions of medicinal herbs has been developed.The contents of FA in decoctions of Rhizoma chuanxiong,Rhizoma chuanxiong and Radix Salviae miltiorrhizae,Rhizoma chuanxiong and Radix Angelica sinensis,and modified"siwutang"were determined by this Rp-HPLC method.Results showed that the contents of FA in these decoctions differed significantly(P＜0.001).An increased extraction rate of FA was obtained with the compatibility of Radix Rehmannise,which acted as a solubilizing agent for FA.

国家自然科学基金(No39100139)