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[摘要]
采用大鼠海马缺血再灌注模型,观察蝙蝠葛碱的抗氧化作用。结果表明,蝙蝠葛碱能明显降低大脑海马结构组织中MDA的含量,显著提高SOD活力和GSH-PX活力,SOD/MDA比值和GSH/MDA比值显著升高,提示蝙蝠葛碱具有明显的抗氧化作用。
[Key word]
[Abstract]
Antioxidaxion effects of Dau on cerebral hippocampal ischemia-reperfusion model in rats were investigated. Results showed that the content of MDA was lowered while the activities of SOD and GSH-PX were raised in hippocampal construction tissue significantly by Dau. In addition,the ratio of SOD/MDA and GSHPX/MDA were significantly increased. These results indicated that Dau may have significant antioxidation activities.
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