三七三醇皂甙（PTS）在体外（1~4mg/ml）和体内十二指肠给药（75~300mg/kg）都明显抑制由ADP、胶原、花生四烯酸（AA）诱导的大鼠及家兔血小板聚集，同时亦抑制胶原诱导大鼠血小板TXA2释放，而对大鼠胸主动脉壁PGI2生成无明显影响。PTS（50~200mg/kg）明显抑制大鼠实验性血栓形成，剂量与效应相关。提示：PTS抗血栓作用与其抑制血小板聚集和TXA2释放有关。

Panaxatriol saponin（PTS), isolated from Panaz pseudo-ginseng var.notoginseng, l~4mg/ml inhibited rabbit platelet aggregation induced by ADP,collagen and arachidonic acid respectively in vitro. In rat,PTS75~300mg/kg intraduodenally inhibited dose-dependently platelet aggregation induced by these inducers，andalso inhibited platelet thrombonane AZ release induced by collagen,but didnot affect the formation of aortic wall PGIZ,PTS50~200mg/kg significantly inhibited experimentALThrombosis in rats. These results showed that the anti-thrombosis action of PTS may be due to its inhibitory action on platelet aggregation and TXAZ release.