观察中药制剂生血灵的止血和药理等作用。结果：生血灵能缩短小鼠的出、凝血时间；增加血小板数；增加家兔骨髓产板型巨核细胞；增加大鼠血浆皮质醇含量；延长小鼠负重游泳时间；增加未成年小鼠体重和肝肾脏器重量。提示生血灵的止血作用与其促进骨髓巨核细胞的分化成熟，增加血小板，加速止血，凝血，调节内分泌功能有关，区安全无毒。

Pharmacology of Shenxueling(SXL),a traditional Chinese medicine used for the treatment of idiopathic thrombocytopenic purpura, and its hemostatic acrivity were studied in experimental animals. Rsultes showed that SXL shortend the time of bleeding and coagulation, raised BPC in mice,increased platelet megakaryocyte production in rabbit, prolong the time of swiming of loaded mice, increased body liver and kidney weights of young mice, increased plasma cortisol level. Acute and chronic toxicity tests revealed that SXL was nontoxic to mice or raats.These results suggested that hemostasis was associated with effects of SXL which could facilitate division and maturity of megakaryocyte, increase the BPC, accelerate coagulation and regulate the function of endocrine.SXL could resist fatigue, endure hypoxia,facilitate growth.It is safe and nontoxic in its use of SXL.

国家中医药管理局基金