以24月龄SD大鼠为对象，观察参芪合剂（由党参、黄芪、何首乌组成）对动物体重，摄食，产热量，心脏功能及脑单脸氧化酶-B（MAO－B），红血细胞超氧化物歧化酶（SOD）活力的影响。结果表明，服用参芪一定时间后，脑中MAO－B活力明显降低。红血细胞SOD活力显著升高。老龄机体在不增加体重的情况下产热率及耐寒能力明显提高。心脏功能得到加强。提示参芪合剂具有较好的抗衰老作用。

Shenqi mixture tonic(C. A. mixture)is a compounded Chinese herb preparation composed of Codonopsispilosula(Franch. )Nannf. ,Astragalus membranaceus Bge. and Polygonum multiflorum Thunb. Its antiaging ef-feet was studied on 24 months old SD rats. The body weight,food intake,cardiac capacity and activities of brain monoamine oxidase-B(MAO-Band red blood cell superoxide dismutase(SOD)were estimated to assessits antiaging effect. Results indicated that after feeding C. A. mixture for a fixed time the activity of MAO-Bwas decreased and that of red blood cell SOD increased obviously. Calorie production and cold resistant capab-bility of the aged animals were improved significantly though there were no gain in body weight. In addition，the cardiac capacity was enhanced. From the above results it can be concluded that C. A. mixture possesses ev-ident antiaging effect.