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[摘要]
给猫腹腔注射柴胡皂鞴注射液1ml/kg和朱砂安神丸1丸灌胃,以眼球运动电图(EOG),大脑皮层电图(EEG),肌电图(EMG)和丘脑外侧膝状体放电(PGO)为电生理学指标,用多导仪连续记录6h。发现柴胡皂甙可延长猫的睡眠时间,特别是慢波睡眠Ⅱ期(ⅡSWS)和快动服睡眠期(REM)的增加与给药前比较均有非常显著性差异。其作用优于经典的朱砂安神丸。
[Key word]
[Abstract]
Effect of saikosaponins on sleep [slow wave-stage Ⅰ(Ⅰ SWS), slow wave -stage Ⅱ(Ⅱ SWS)rapid eye movement, REM] were studied in cats. Electrophysiological recording of EOG,EEG, EMG and PGO were monitored by polygraph for six consecutive hours. Preparation of saikosaponins was injected intraperitoneally. Results showed that saikosaponins could prolong total sleeping time, Ⅱ SWS and REM time. The effect of saikosaponins is better than "zhushaanshen pill" by gastric gavage.
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