选取丹参、丹皮等11味具有抗氧化作用的中药组成“抗氧化复方”，以大鼠束缚水浸应激性胃粘膜损伤为实验病理模型，观察抗氧化中药对应激性损伤的保护作用。结果：中药复方组和丹参注射组的胃粘膜损伤计数分别为8.5±2.31和19±4.24；血清脂质过氧化物（LPO）分别为10.74±0.94和11.80±1.06（nmol/ml），均较对照组（损伤计数39±6.50，LPO19.06±1.10nmol/ml）显著减轻（P＜0.05）。初步证明抗氧化中药对应激性损伤有保护作用，复方效果可能优于单味药。

Protective effect of Chinese medicinal herbs against gastric stress injury was studied.The compound antioxidant prescription used was composed of ten herbs, each of which had proven antiperoxidation action. Bound-soaked rats were used as victims of stress injury. In the two groups of rats under protection of the "prescription and injection of salvia" the index-en of gastric mucosa injury were 8.5012.31 and 19,00±4.25, LPO in serum were 10.7410.94 and 11.8011,06amo1/ml respectively, Both were significantly decreased as compared with the co-ntrol group(ss.oofs.so, LPO ls.os±1, l0amol/ml)。These results signified that the antioxid-ant medicinal herbs, especially in compounded form, may prevent gastric stress.

TQ460.72