目的 探讨阿托伐他汀致不良反应（ADR）的一般规律与特点。方法 对福建省长乐市医院2008年1月—2012年6月上报的阿托伐他汀所致10例ADR报告表进行统计、分析。结果 阿托伐他汀引起的ADR中，女性7例，男性3例。发生次数最多为心肌、心内膜、心包及瓣膜损害3次（17.65%），肝胆系统损害3次（17.65%）、全身性损害2次（11.76%）、中枢及外周神经系统损害2次（11.76%）、胃肠系统损害2次（11.76%）。结论 临床上应加强阿托伐他汀应用的监测，以减少不良反应的发生。

Objective To explore statin adverse reactions(ADR) caused by the general rules and characteristics of atorvastatin. Methods atorvastatin due to Fujian Changle Hospital hospital from January 2008—June 2012 reported 10 cases of ADR reports statistical analysis. Results atorvastatin total of 10 cases of statin induced adverse reaction, more women than men. Due to adverse reactions occurred most frequently myocardial, endocardial, pericardial and valvular damage three times (17.65%), the hepatobiliary system damage (17.65%), the systemic damage 2 times (11.76%), the central and peripheral nervous system damage to 2 times (11.76%), gastrointestinal system damage (11.76%). Conclusion should strengthen the clinical atorvastatin statins application monitoring, in order to reduce the occurrence of adverse reactions.