[关键词]
[摘要]
肠道菌群作为人体内一个复杂的微生态系统,在维持宿主生理功能上起非常重要的作用,也与许多代谢性疾病、免疫性疾病有着密切的关系。分析睡眠剥夺与肠道菌群紊乱相关性研究的提出和再提出,综合分析肠道菌群紊乱与睡眠障碍的关系,为以肠道菌群为靶点的改善睡眠药物开发及防治方法与思路提供参考。
[Key word]
[Abstract]
As a comlex microecosystem, gut microbiota plays an important role in maintaining the host physiological function and is also closely related to many metabolic diseases and immune diseases. In this review, we comprehensively analyze the relationship between gut microbiota disorder and sleep disturbances, based on the two times emerging researches of the correlation between sleep deprivation and gut microbiota disorder over the past few decades. The analysis may provide indication for drug development and prevention approaches targeting gut microbiota to improve sleep.
[中图分类号]
[基金项目]
国家自然科学基金面上项目(81274114)