黄皮树Phellodendron chinense、黄檗P.amurense的干燥树皮分别作为黄柏、关黄柏入药，二者在2005、2010、2015年版《中国药典》被分别收录。从这两种药材中分离出来的化学成分主要包括生物碱类、柠檬苦素类、酚酸类、萜类、苯丙素类、挥发性类等，具有抗菌、抗癌、抗糖尿病、保护心脑血管等多种生物活性。综述近年来对黄柏、关黄柏化学成分、生物活性的研究进展，为进一步研究两者药效物质基础、药理作用及临床合理用药提供参考依据。

The original plant of Phellodendri Chinensis Cortex was Phellodendron chinense, and the original plant of Phellodendri Amurensis Cortex was P. amurense. The two kinds of medicinal materials were recorded in the Pharmacopoeia of China in the 2005, 2010, 2015 edition as different species, and the chemical constituents isolated from the two medicinal materials mainly include alkaloids, limonoids, phenolic acids, terpenoids, phenylpropanoids, volatiles. They had many biological activities, such as antibacterial, anti-cancer, anti-diabetes, protection of cardiovascular and cerebrovascular. Recent advances in chemical constituents and biological activities of Phellodendri Chinensis Cortex and Phellodendri Amurensis Cortex were reviewed, which could provide references for further study on the pharmacodynamic material basis, pharmacological effects and rational clinical use of drugs with Phellodendri Chinensis Cortex and Phellodendri Amurensis Cortex.

中央本级重大增减支项目（2060302）；国家中医药优势特色教育培训基地（中药）资助项目（J20164811007）