帕金森病（Parkinson's Disease，PD）是中老年人常见的神经系统变性疾病，其发病可受年龄、遗传和环境等因素影响，其主要病理机制为大脑黑质致密部多巴胺能神经元的病变缺失。保护多巴胺能神经元是行之有效的方法之一，脑内炎症反应、氧化应激等均可导致神经细胞的损伤。杜仲是常用补益中药，具有明确的神经保护作用，临床常用于PD的治疗，对近年杜仲及其有效成分在PD治疗中的药理作用研究进展做一综述，以期为杜仲在防治PD方面的开发应用提供一定线索。

Parkinson's disease (PD) is a common neurodegenerative disease in the elderly people. Its pathogenesis can be affected by age, heredity and environment. Its main pathological mechanism is the loss of dopaminergic neurons in the substantia nigra. Protecting dopaminergic neurons is one of the effective methods. Inflammatory reaction and oxidative stress in brain can lead to damage of nerve cells. Eucommia ulmoides Oliv. is precious tonic herbs of traditional Chinese medicine with definite neuroprotective effect. It is commonly used in the treatment of PD in clinic. In this paper, the pharmacological effects and effective components in the treatment of PD in recent years are studied. This review will provide a clue for the development and application of Eucommia ulmoides Oliv. in the prevention and treatment of PD.

国家自然科学基金（81703827）