目的 建立快速鉴别地榆及其炮制品地榆炭配方颗粒的红外方法。方法 采用红外光谱结合二阶导数光谱及二维相关光谱法分析地榆及其炮制品配方颗粒的光谱特征。结果 地榆与炮制品配方颗粒的红外光谱基本相似，仅在2 932、1 041、918、760 cm^-1处位置变化；二阶导数光谱在1 200～1 800 cm^-1差异较大，二维相关光谱图差异明显。结论 通过比较地榆及其炮制品红外光谱图、二阶导数光谱图及二维相关光谱图，可以准确、快速鉴别地榆及其炮制品地榆炭配方颗粒。

Objective To establish a rapid FTIR method for identifying of different processed products of Sanguisorbae Radix Formula Granules. Methods Different processed products of Sanguisorbae Radix Formula Granules were researched by infrared、second derivative spectra and two-dimensional correlation spectroscopy.Results The infrared spectra of two formula granules were similar, while the position of the peaks were different in 2 932, 1 041, 918, 760 cm^-1. In second derivative spectra, the intensity, shape and position of the peaks were different in the range of 1 200-1 800 cm^-1, Two-dimensional correlation spectroscopy were obvious difference. Conclusion By comparing the infrared spectra, second derivative spectra and two-dimensional correlation spectroscopy of different processed products. It can be identified rapidly and accurately of different processed products of Sanguisorbae Radix Formula Granules.

河北省高等学校科学技术研究重点项目（ZD2015001）；河北省中医药管理局科研计划项目（2017013）