目的 运用CiteSpace软件对苍术Atractlodis Rhizoma的研究热点及发展趋势进行可视化分析，为其深入研究提供参考。方法 分别检索中国学术期刊全文数据库（CNKI）、Web of Science数据库中收录的，2003年1月1日—2024年12月31日苍术相关研究文献，运用CiteSpace 6.3.R1软件对发文作者、研究机构、关键词共现、关键词突现等内容进行可视化图谱分析，并对苍术研究现状及发展趋势进行分析归纳。结果 筛选后共纳入861篇中文文献，339篇英文文献，中、英文文献年发文量均呈震荡波动上升趋势；《中成药》《Journal of Ethnopharmacology》分别是发表中文和英文文献最多的期刊，刘艳菊、Dai Chuanchao分别是发表中文和英文文献最多的作者，发文量较高的研究机构为中国中医科学院（China Academy of Chinese Medical Sciences）、湖北中医药大学、南京中医药大学、南京师范大学（Nanjing Normal University），机构间形成一定合作规模；关键词分析显示，频次较高且中介中心性较强的关键词有“苍术”“苍术素”“茅苍术”“ expression”“rhizomes”“apoptosis”等，中文关键词研究热点聚焦于传统中药的品种鉴别、道地性特征及药效物质基础；英文关键词研究热点则集中于分子机制探索、细胞生物学效应及活性成分的药理作用路径。关键词共生成19个聚类归纳出以下5个研究热点：苍术资源与种植、质量评价与鉴别、炮制相关与机制研究、药理作用与机制研究、临床应用及配伍疗效。结论 现阶段已对苍术功效、药理作用、炮制机制和栽培种植等方面进行深入研究，但仍在持续发展阶段，特别是在苍术种植栽培、炮制降燥增效机制、临床疗效评价等方面，研究尚存在不足，未来仍有较大的完善空间与深度挖掘价值。

Objective To research hotspots and development trends of Cangzhu (Atractylodis Rhizoma), so as to provide references for in-depth investigations into this medicinal herb. Methods Literature related to Atractylodis Rhizoma published between January 1, 2003, and December 31, 2024, was retrieved from the China National Knowledge Infrastructure (CNKI) and Web of Science databases. Using CiteSpace 6.3.R1 software, the data were systematically organized and visually analyzed to generate co-authorship networks, institutional collaboration maps, keyword co-occurrence clusters, and bursty keyword detection. This study synthesizes the current research landscape and future trends in Atractylodis Rhizoma research, providing a comprehensive reference for in-depth investigations. Results A total of 861 Chinese literatures and 339 English literatures were included through screening. The annual number of published papers shows an oscillating upward trend. Chinese Journal of Traditional Patent Medicine and Journal of Ethnopharmacology were the journals with the most publications in Chinese and English, respectively. Liu Yanju and Dai Chuanchao were the authors with the most publications in Chinese and English, respectively. The research institutions with high publication volumes included China Academy of Chinese Medical Sciences, Hubei University of Chinese Medicine, Nanjing University of Chinese Medicine, and Nanjing Normal University, forming a certain scale of cooperation among institutions. Keyword analysis showed that keywords with high frequency and strong betweenness centrality included "Cangzhu", "Atractylodin", "Atractylodes lancea", "expression", "rhizome", "apoptosis", etc. The research hotspots of Chinese keywords focused on the variety identification, genuine characteristics, and pharmacodynamic material basis of traditional Chinese medicine, while the research hotspots of English keywords concentrated on the exploration of molecular mechanisms, cell biological effects, and pharmacological action pathways of active ingredients. A total of 19 clusters were generated from the keywords, which were summarized into the following 5 research hotspots: Atractylodis Rhizoma resources and cultivation, quality evaluation and identification, processing-related and mechanism research, pharmacological effects and mechanism research, clinical application and compatibility efficacy. Conclusion At present, in-depth research has been carried out on the efficacy, pharmacological effects, processing mechanisms, and cultivation of Atractylodis Rhizoma However, it is still in a stage of continuous development. Especially in aspects such as the cultivation of Atractylodis Rhizoma, the mechanism of reducing dryness and enhancing efficacy in processing, and the evaluation of clinical efficacy, There are still deficiencies in the research, and there is still considerable room for improvement and potential for in-depth exploration in the future.

R282.71

国家自然科学基金资助项目（82360771）；国家重点研发计划“中医药现代化研究”重点专项（2023YFC3504205）；特色炮制技术规律发掘——麸制项目（GZY-KJS-2022-051）；中药炮制技术传承创新团队项目（CXTD22003）；中药炮制（炆法）等关键技术重点研究室项目（赣中医药科教字〔2022〕8号）；江西省“双千人才”计划项目［赣才办字（2019）9号］；江西省中医药产业科技创新联合体产业链协同攻关项目（20224BBG72001）；江西省自然科学基金项目（20224ACB206048）；中药炮制传承创新与转化江西省重点实验室项目（2024SSY07091）；建昌帮特色饮片炮制工艺及质量标准规范化研究项目（JCB-202302-033）；江西省标准创新基地（医药）