[关键词]
[摘要]
目的 利用CiteSpace 6.1.R6软件对2005—2024年关于中药治疗脑卒中的国内外文献进行文献计量学及可视化分析,深入探讨该领域的研究现状及未来趋势,为未来的基础研究和临床研究提供参考依据。方法 通过中国学术期刊全文数据库(CNKI)、万方数据库(Wanfang)、维普生物医学数据库(VIP)检索中文文献,以及Web of Science(WOS)检索英文文献,对收集到的数据进行作者、机构及关键词的深入分析。结果 共检索到中文文献1 312篇和英文文献1 582篇,其中英文文献发文量呈现上升趋势,而中文文献发文量则相对稳定。作者合作网络分析揭示了研究团队间的交流合作,但整体合作密度有待提高;机构间存在广泛的跨国与跨省合作,以国内中医药大学及其附属医院为主要研究力量。关键词共现分析指出,利用分子对接和网络药理学手段研究中药治疗脑卒中已成为热点,控制氧化应激成为治疗脑卒中的重要方向,丹参、黄芪等中药在治疗中展现出显著价值。结论 中药治疗脑卒中在临床和基础研究中已取得一定成果,但未来仍需加强跨领域合作与深入研究,以期进一步挖掘其潜力并推动该领域的持续发展。
[Key word]
[Abstract]
Objective To conduct bibliometric and visualization analysis of domestic and international literature on traditional Chinese medicine (TCM) treatment for stroke from 2005 to 2024 using CiteSpace 6.1.R6 software. To provide insights into the current research status and emerging trends in this field, serving as a reference for future basic and clinical research. Methods Literature search was conducted across Chinese databases including China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (Wanfang), and China Science and Technology Journal Database (VIP), as well as Web of Science (WOS) for English literature. Authors, institutions, and keywords were analyzed in depth using the retrieved data. Results A total of 1 312 Chinese articles and 1 582 English articles were retrieved. The publication volume of English articles showed an upward trend, while that of Chinese articles remained relatively stable. The author collaboration network analysis revealed interactions and cooperation among research teams, though the overall cooperation density could be improved. Extensive transnational and interprovincial collaborations were observed, with domestic universities of traditional Chinese medicine and their affiliated hospitals serving as the main research forces. The keyword co-occurrence analysis indicated that utilizing molecular docking and network pharmacology to study TCM treatment for stroke has become a research hotspot, and controlling oxidative stress emerged as a crucial direction in stroke treatment. TCM such as Salviae Miltiorrhizae Radix et Rhizoma and Astragali Radix have demonstrated significant value in treatment. Conclusion TCM treatment for stroke has achieved certain accomplishments in both clinical and basic research. However, future endeavors should focus on strengthening cross-disciplinary collaboration and in-depth research to further tap into its potential and propel sustainable development in this field.
[中图分类号]
R971
[基金项目]
国家自然科学基金青年项目(82301725);中国博士后科学基金第73批面上资助项目(2023M732155);山西省基础研究计划面上项目(202203021212028);山西省卫生健康委中医药科研项目(2023ZYYC2034,2024ZYYB054);山西省高等学校科技创新项目(2022L132);山西省科技厅基础研究项目(20210302124586);山西省归国留学人员资助项目(2023-177);山西省高等学校科技创新项目资助项目(2023W185)