目的 从文献计量学的角度对黄连中、英文文献的研究现状及热点进行全面分析，为未来黄连的临床应用和深入研究提供理论指导。方法 以黄连为关键词检索中国学术期刊全文数据库（CNKI）、万方数据库（Wanfang Data）、维普数据库（VIP）、Web of Science（WOS） 4个数据库，将文献导入NoteExpress文献管理软件中进行查重和筛选。使用Excel、CiteSpace、VOSviewer等软件，从发文趋势与国家分布、发文机构、发文作者、关键词等维度出发，对国内外黄连研究进行可视化分析。结果 共检索到符合要求的中文文献3 277篇，英文文献2 193篇，发文国家以中国为主，已构建具有核心凝聚力的研究团队体系；近年来，中、英文文献研究的热点领域存在一定重叠，均涉及网络药理学、分子对接等生物信息学方向，重点关注了肠道菌群、溃疡性结肠炎的研究。结论 黄连领域的研究正不断拓展和深入，有望进一步强化多学科交叉融合，提升中医药理论与临床实践的科学性和有效性。

Objective From the perspective of bibliometrics, this study conducts a comprehensive analysis of the research status and hotspots in Chinese and English literatures on Coptidis Rhizoma, aiming to provide theoretical guidance for the clinical application and in-depth research of Coptidis Rhizoma in the future. Methods Taking “Coptidis Rhizoma” as the key term, literature retrieval was performed in four databases, including CNKI, Wanfang, VIP, and Web of Science (WOS). The retrieved literatures were imported into the NoteExpress reference management software for duplicate checking and screening. Software such as Excel, CiteSpace, and VOSviewer was used to conduct visual analysis on domestic and international studies of Coptidis Rhizoma from multiple dimensions, including literature publication trends, national distribution of publications, contributing institutions, authors, and keywords. Results A total of 3 277 eligible Chinese literatures and 2 193 eligible English literatures were retrieved. China was the dominant country in terms of publication output, and a research team system with core cohesion has been established. In recent years, there was a certain overlap in the research hotspots between Chinese and English literatures, both involving bioinformatics directions such as network pharmacology and molecular docking, with a focus on studies related to intestinal flora and ulcerative colitis. Conclusion Research in the field of Coptidis Rhizoma is continuously expanding and deepening. It is expected to further strengthen the integration of multiple disciplines and enhance the scientificity and effectiveness of traditional Chinese medicine theory and clinical practice.

R285.5

国家社科基金冷门绝学项目（21VJXG038）；国家中医药管理局高水平中医药重点学科建设项目（ZYYZDXK-2023073）；江苏省中医流派研究院重点课题（LPZD2025014）；江苏省中医流派研究院开放课题（JSZYLP2024044）；江苏高校优势学科建设工程资助项目（PAPD）