[关键词]
[摘要]
目的 基于CiteSpace和VOSviewer系统分析中药挥发油研究现状与发展趋势,为其深入研究提供参考。方法 检索中国学术期刊全文数据库(CNKI)、维普生物医学数据库(VIP)、万方数据库(Wanfang Data)、Web of Science(WOS)4个数据库,筛选2001年1月1日至2025年12月10日中药挥发油相关文献,利用Excel、CiteSpace、VOSviewer软件,对文献发文量、研究国家、发文机构、核心作者、关键词等核心指标进行文献计量及可视化分析。结果 共纳入符合要求的中文文献5 350篇、英文文献934篇。文献计量结果显示,中文文献的整体趋势表现为先升后降,而英文文献则持续呈现上升趋势,共同构建了以中国为核心的多维度合作格局。中、英文发文量最高的机构均为成都中医药大学,中文文献核心作者为杨明,英文文献核心作者为Deng Chunhui。关键词分析显示,国内外在中药挥发油研究领域主要集中在提取方法的创新与优化、组分分析、质量控制、药理作用及其机制的探讨。其中中文文献还涉及道地药材,以及中医理论指导下复方中药挥发油作用机制等研究方向。结论 中药挥发油研究体系已日趋完善,中西医研究视角互补融合。未来该领域将聚焦绿色制备工艺、稳定化技术与新型递药制剂创新,持续深化药理机制研究、构建标准化质量控制体系,并积极向农业、食品等新兴领域拓展应用边界,实现多学科交叉创新发展。
[Key word]
[Abstract]
Objective To analyze the current status and development trends of research on volatile oils from traditional Chinese medicine (TCM) using CiteSpace and VOSviewer, providing reference for further studies. Methods Literature related to TCM volatile oils was retrieved from four databases-China National Knowledge Infrastructure (CNKI), VIP, Wanfang, and Web of Science (WOS)-covering publications from January 1st, 2001, to December 10th, 2025. Using Excel, CiteSpace, and VOSviewer software, bibliometric and visualization analyses were conducted on key indicators including publication volume, countries involved, institutions, core authors, and keywords. Results A total of 5 350 Chinese articles and 934 English articles met the inclusion criteria. Bibliometric analysis revealed that the trend in Chinese publications showed an initial increase followed by a decline, while English publications demonstrated a continuous upward trend, collectively forming a multidimensional collaborative network centered in China. Chengdu University of Traditional Chinese Medicine ranked highest in both Chinese and English publications; Yang Ming was identified as the core author in Chinese literature, while Deng Chunhui was the core author in English literature. Keywords analysis indicated that research in both domestic and international contexts primarily focused on innovation and optimization of extraction methods, component analysis, quality control, pharmacological effects, and their underlying mechanisms. Additionally, Chinese literature also covered topics such as authentic medicinal materials and the mechanisms of volatile oils from compound prescriptions guided by TCM theory. Conclusion The research system on TCM volatile oils has become increasingly comprehensive, with complementary integration between Eastern and Western perspectives. Future research will focus on green preparation technologies, stabilization techniques, and innovations in drug delivery systems, deepen investigations into pharmacological mechanisms, establish standardized quality control systems, and actively expand applications into emerging fields such as agriculture and food science, promoting interdisciplinary innovation and development.
[中图分类号]
R285.5
[基金项目]
云南省孔令义专家工作站(202605AF350055);国家自然科学基金资助项目(82174065);云南省朱兆云院士工作站(202405AF140128);云南省科技厅社会发展专项-重点研发计划项目(202303AC100025);云南省生物医药专项-重大科技专项计划(202302AA310031)