目的 基于文献计量学方法，系统解析蒲黄的研究现状、演进脉络及前沿热点，为该药材的深入研究与多元化开发提供数据支撑。方法 检索2000年1月—2025年12月中国学术期刊全文数据库、万方、维普及Web of Science核心合集数据库中的蒲黄相关文献，运用Excel、CiteSpace及VOSviewer软件，对发文量、发文国家、期刊、作者、机构及关键词开展可视化分析。结果 共纳入有效中文文献929篇、英文文献232篇。中文文献发文量于2008年达峰值后呈波动趋势，英文文献发文量则逐年稳步上升；中国为蒲黄国际研究的发文量首位国家，南京中医药大学在中、英文发文机构中均排名第一；中文文献核心作者以丁安伟、陈佩东、张丽等为代表，英文文献核心作者以Vangansbeke, Dominiek、De clercq, Patrick等为代表。二者研究热点差异显著，中文文献聚焦临床应用与研究方法、炮制工艺及质量控制，英文文献则侧重农业生态领域的生物防治，重点探究香蒲花粉作为捕食螨替代食源的应用价值，且近期已逐步关注蒲黄成分表征研究。结论 蒲黄的中、英文研究形成“临床药用-生态农业”的双向发展格局，其中中文研究正从经验总结向“炮制-质控-机制”的链条化方向深入，英文研究进一步拓展了蒲黄的生态资源价值。该领域未来研究热点将集中于炮制工艺标准化、多维质量评价体系构建及基于临床数据的药效机制解析。

Objective Based on bibliometric methods, this study systematically analyzed the current research status, evolution trajectory, and frontier hotspots of Typhae Pollen, providing data support for in-depth research and diversified development of this medicinal material. Methods Relevant literature on Typhae Pollen from 2000 to 2025 was retrieved from the China Academic Journal Full-text Database, Wanfang, WIP, and the Web of Science Core Collection Database. Excel, CiteSpace, and VOSviewer software were used to conduct visual analysis of the number of publications, countries, journals, authors, institutions, and keywords. Results A total of 929 valid Chinese literature and 232 English literature were included. The number of Chinese publications reached a peak in 2008 and then fluctuated, while the number of English publications steadily increased year by year. China was the leading country in the number of international publications on Typhae Pollen. Nanjing University of Chinese Medicine ranked first in both Chinese and English publishing institutions. The core authors of Chinese literature were represented by Ding Anwei, Chen Peidong, Zhang Li, etc., while the core authors of English literature were represented by Vangansbeke, Dominiek, De clercq, Patrick, etc. The research hotspots of the two languages were significantly different. Chinese literature focused on clinical application and research methods, processing techniques, and quality control, while English literature focused on biological control in the agricultural ecology field, mainly exploring the application value of Phragmites pollen as an alternative food source for predatory mites, and has gradually paid attention to the characterization study of Typhae Pollen components in recent times. Conclusion The Chinese and English studies on Typhae Pollen have formed a “clinical use-ecological agriculture” two-way development pattern. Among them, the Chinese research is moving from experience summary to a chain-like direction of “processing-quality control-mechanism”, while the English research has further expanded the ecological resource value of Typhae Pollen. The future research hotspots in this field will focus on standardization of processing techniques, construction of multi-dimensional quality evaluation system, and interpretation of pharmacological mechanism based on clinical data.

R285

国家自然科学基金面上项目(82574969)