目的 基于CiteSpace和VOSviewer文献计量学方法，分析岭南药食同源中药五指毛桃Ficus hirta的现状并预测未来的研究热点和发展趋势，以推动岭南药食资源标准化、国际化发展。方法 检索Web of Science核心合集（WoSCC）与中国学术期刊全文数据库（CNKI）自建库至2025-07-30的中、英文文献，利用CiteSpace 6.4 R1与VOSviewer 1.6.20开展文献计量分析，通过发文量、国家/地区、机构、作者、期刊及关键词共现、聚类、时间线、突现等数据与图谱，揭示其研究的演进路径。结果 共纳入1960—2025年间的836篇文献（中文717篇、英文119篇）；中文发文量2018年后受“药食同源”政策驱动，2024年达56篇峰值；英文发文量2022年后稳定在年约10篇。中国在该领域研究中占据核心地位，国内形成以广州中医药大学、广西中医药大学为核心的岭南研究集群，国际合作则相对有限。关键词演化呈现国内外差异化路径，国际为“物种生态-功能发现-应用开拓”，国内为“物质基础-临床经验-数据驱动”； 2017年后“数据挖掘”“肠道菌群”等成为新研究热点。研究已从鉴定补骨脂素、多糖等130余种化合物，拓展到验证其抗炎、免疫调节、保肝等多靶点功能。结论 五指毛桃研究在政策与市场需求双轮驱动下快速发展，未来研究需聚焦优良种质培育与全过程质量标准构建、深入多组学机制研究与循证转化、创新功能产品及推进国际化开发，推动其成为岭南特色药食资源的标杆。

Objective Based on the bibliometric methods of CiteSpace and VOSviewer, this study analyzes the current situation of the medicinal and edible plant Ficus hirta from Lingnan region and predicts the future research hotspots and development trends, aiming to promote the standardization and internationalization development of Lingnan medicinal and edible resources. Methods We retrieved Chinese and English literature from the Web of Science Core Collection (WoSCC) and the China Academic Journal Full-text Database (CNKI) from the establishment of the databases to July 30, 2025. CiteSpace 6.4 R1 and VOSviewer 1.6.20 were used for bibliometric analysis. Through data such as publication volume, countries/regions, institutions, authors, journals, co-occurrence of keywords, clustering, timeline, and emergent phenomena, the evolution path of the research was revealed. Results A total of 836 documents (717 in Chinese and 119 in English) were included from 1960 to 2025. The number of Chinese publications increased after 2018, driven by the “medicinal and edible homology” policy, reaching a peak of 56 in 2024; the number of English publications remained stable at approximately 10 per year after 2022. China holds a core position in this field of research, and a Lingnan research cluster centered on Guangzhou University of Chinese Medicine and Guangxi University of Chinese Medicine has formed domestically. International cooperation is relatively limited. Keywords evolution presents different paths at home and abroad , with international being “species ecology-functional discovery-application exploration” and domestic being “material basis-clinical experience-data-driven”; since 2017, “data mining" and” “intestinal microbiota” have become new research hotspots. The research has expanded from identifying more than 130 compounds such as psoralen and polysaccharides to verifying their anti-inflammatory, immunomodulatory, and liver-protective multi-target functions. Conclusion The research on Ficus hirta Vahl has rapidly developed under the dual drive of policies and market demands. Future research should focus on the cultivation of excellent varieties and the construction of the entire process quality standards, in-depth multi-omics mechanism research and evidence-based transformation, innovation of functional products, and promotion of international development, to make it a benchmark of Lingnan characteristic medicinal and edible resources.

R282.71;G353.1

广西科技计划项目“赋能”行动计划（广西重点研发计划）（桂科FN2600640142）；国家中医药管理局高水平中医药重点学科建设项目/少数民族医学（壮医学）（zyyzdxk-2023164）；国家中医药管理局国家中医优势专科建设单位项目（国中医药医政函[2024]90号）；第六批广西中医骨伤临床医学研究中心（桂科发〔 2024〕 158号）