目的 从文献计量学的角度对胶类中药的研究现状和热点进行可视化分析，为未来胶类中药的深入研究提供理论指导。方法 检索中国学术期刊全文数据库（CNKI）、万方数据库（Wanfang Data）、维普生物医学数据库（VIP）、Web of Science(WOS)4个数据库，将文献导入Note Express文献管理软件中进行查重和筛选。使用Excel、CiteSpace等软件，从发文趋势、发文机构、发文作者、关键词等维度出发，对国内外胶类中药研究现状进行可视化分析。结果 共检索到符合条件的中文文献1 124篇，英文文献125篇。胶类中药研究呈现出持续发展态势，发文国家以中国为主，近些年国际关注度逐渐提高。胶类中药领域的核心团队已经初步形成，相关合作多开展于机构内部或同一地区，跨区域合作较少。胶类中药领域的中文文献与英文文献均重点关注胶类中药的质量控制、药理作用、作用机制、肠道菌群等方面。中文文献更多关注胶类中药的质量标准、工艺优化等方面，英文文献则更多关注胶类中药的分子对接、特征肽等方面。结论 对胶类中药的质量控制、作用机制的关注度持续上升，分子对接、体内外机制研究为胶类中药的研究提供新的突破口。未来应运用更加先进的研究技术，深入探讨胶类中药作用机制，并建立胶类中药国际化质量标准，以推动胶类中药高质量发展。

Objective To conduct a visual analysis of the research status and hotspots of gelatin-based traditional Chinese medicines from a bibliometric perspective, with the aim of providing theoretical guidance for future in-depth research and application of these medicines. Methods Four databases-China National Knowledge Infrastructure(CNKI), Wanfang, VIP, and Web of Science(WOS) were searched and imported the literature into Note Express for deduplication and screening. Excel and CiteSpace were used to perform a visual analysis of domestic and international research on gelatin-based traditional Chinese medicines, focusing on publication trends, institutions, authors, and keywords. Results A total of 1 124 Chinese and 125 English publications meeting the criteria were retrieved. Research on gelatin-based traditional Chinese medicines has shown continuous development, with China being the primary contributing country, though international attention has gradually increased in recent years. Core research teams in this field have begun to form, with collaborations mostly occurring within institutions or the same region, and cross-regional cooperation being relatively limited. Both Chinese and English literature in this field focus on quality control, pharmacological effects, mechanisms of action, and gut microbiota related to gelatin-based traditional Chinese medicines. Chinese literature places more emphasis on quality standards and process optimization, while English literature tends to focus more on molecular docking and characteristic peptides. Conclusion Interest in the quality control and mechanisms of action of gelatin-based traditional Chinese medicines continues to rise. Molecular docking and in vivo and in vitro mechanism studies have provided new breakthroughs for research in this field. In the future, more advanced research technologies should be applied to further explore the mechanisms of action of gelatin-based traditional Chinese medicines and establish international standards to promote their high-quality development.

R282.74

山东省重点研发计划资助项目(2025CXPT123)