桑黄是一种应用广泛的药用真菌。现代研究表明桑黄的化学成分主要为多糖、酚酸、黄酮、萜类、甾体等，具有抗炎、抗肿瘤、镇静催眠、降血糖等多种药理作用。基于桑黄化学成分和药理作用的研究进展，从物质功效关联性、有效性、特有性、可测性及传递性，对桑黄质量标志物（Q-Marker）进行推测，预测麦角甾醇、phellibaumin D及包括桑黄素、花旗松素等在内的黄酮类成分可能为桑黄Q-Marker的候选成分。

Phellinus igniarius (Sanghuang) is a widely used medicinal fungus. Modern research indicates that its chemical components primarily include polysaccharides, phenolic acids, flavonoids, terpenoids, steroids, and others, which exhibit diverse pharmacological activities such as anti-inflammatory, anti-tumor, sedative-hypnotic, and hypoglycemic effects. Based on advances in the study of its chemical composition and pharmacological properties, this paper evaluates potential quality markers (Q-Marker) for Sanghuang by analyzing substance-efficacy correlations, effectiveness, specificity, measurability, and transferability. It is hypothesized that ergosterol, phellibaumin D, and flavonoid constituents such as sanghuangin and taxifolin may serve as candidate Q-Marker for Sanghuang.

R969.2

国家自然科学基金资助项目（82274091）