气相色谱-离子迁移谱（GC-IMS）是一种可快速分离挥发性气体并灵敏检测挥发性有机成分（VOCs）的新兴技术，具有操作简单、适用范围广泛等优点。鉴于气味是中药的突出特点且在中药质量评价中占有重要地位，近年来该技术在中药领域的应用频率增长迅速。在介绍GC-IMS技术的原理、相关参数的基础上，对GC-IMS在中药质量评价领域的应用进行了梳理和归纳，包括中药挥发性成分的表征、对中药真伪、基原、产地的鉴别以及根据气味变化对中药采收、贮存时期、加工炮制品的判断等方面，并对该技术目前存在的问题和策略进行了讨论，以期为GC-IMS技术在中药领域深入应用提供参考。

Gas chromatography-ion migration spectrometry (GC-IMS) is a new technology for rapid separation of volatile gases and sensitive detection of volatile organic components (VOCs). It has the advantages of simple operation and wide application. Since odor is a prominent feature of Chinese materia medica (CMM) and plays an important role in the quality evaluation of CMM, the application frequency of this technology in the field of CMM has increased rapidly in recent years. Based on the introduction of the principle and related parameters of GC-IMS technology, the application of GC-IMS in the field of CMM quality evaluation was sorted out and summarized, including the characterization of volatile components of CMM, the identification of authenticity, origin and origin of CMM, and the judgment of harvesting, storage period and processed products of CMM according to odor changes. The existing problems and strategies of GC-IMS technology are discussed in order to provide reference for the further application of GCIMS technology in the field of CCM.

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国家自然科学基金资助项目（81774452，81001646）;河南省卫生健康中青年学科带头人专项（HNSWJW-2020014）;河南省中医科学研究基地专项（2021JDZY036）;国家中医药管理局青年岐黄学者培养项目（国中医药人教函［2022］256号）;河南省中医药科学研究专项（2023ZY2034）;河南省自然科学基金项目杰出青年科学基金项目（242300421023）