目的 通过文献计量学的方法,对《金匮要略》"下瘀血汤"相关文献的关键词进行可视化分析,以探索该领域未来的研究趋势和热点。方法 选取中国知识资源总库(CNKI)、万方数据知识服务平台(Wanfang Data)、维普中文期刊全文数据库(VIP)作为数据来源,以"下瘀血汤"为关键词进行文献检索。运用VOS viewer、Cite Space (6.1.R3)和Excel软件,检索时间从建库至2023年12月31日,对相关文献的关键词频次及其聚类进行分析。结果 共筛选出321篇相关文献用于文献发表量及被引频次变化趋势分析,共筛选出267篇相关文献用于关键词聚类分析。自1978年起,关于"下瘀血汤"的文献发表呈现波动趋势,分别在1995年、2007年和2012年达到高峰。涉及9类关键词聚类,共计25个关键词频繁出现。结论 9类关键词聚类可分为从《金匮要略》原文出发的下瘀血汤的基础理论探讨、下瘀血汤的临床应用及加减用药、下瘀血汤的现代作用机制研究3个研究方向。其中以中医学"血瘀证"的科学内核、子宫内膜异位症、药流不全、肺纤维化、肝癌、中药炮制、方剂剂型等方面为最新的中文研究热点。

Objective Using bibliometric methods, this study conducts a visual analysis of the keywords in the literature related to "Xia Yuxue Decoction" in the "Jingui Yaolue" to explore future research trends and hotspots in this field. Methods The China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, and VIP Chinese Journal Full-text Database were selected as data sources, with "Xia Yuxue Decoction " as the keyword for literature retrieval. VOSviewer, CiteSpace (6.1. R3), and Excel software were employed for analysis. The retrieval period ranged from the establishment of the databases to December 31st, 2023. The frequency of keywords and their clustering in the relevant literature were analyzed. Results A total of 321 relevant literatures were selected for analysis of publication volume and citation frequency trends, while 267 relevant literatures were used for keyword clustering analysis. Since 1978, literature on "Xia Yuxue Decoction" showed fluctuating trends in publication, with peaks in 1995, 2007, and 2012. Nine categories of keyword clusters were identified, with a total of 25 keywords appearing frequently. Conclusion The nine categories of keyword clusters can be divided into three research directions:theoretical exploration of "Xia Yuxue Decoction" based on the original text of the "Jingui Yaolue" clinical applications and modifications of "Xia YuXue Decoction" and modern mechanistic studies of "Xia Yuxue Decoction" Among them, the scientific core of traditional Chinese medicine "blood stasis syndrome," endometriosis, incomplete medication-induced abortion, pulmonary fibrosis, liver cancer, traditional Chinese medicine processing, and formulation types are the latest research hotspots.

R286.2;R289

国家自然科学基金资助项目(82074294);国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]239号)