菲类化合物是石斛属植物的特征成分之一，可分为简单菲、二氢菲、双菲及菲醌（酮）等菲衍生物4种类型。综述了金钗石斛、铁皮石斛、束花石斛、细茎石斛、流苏石斛、密花石斛、鼓槌石斛、曲轴石斛、石斛兰和绒毛石斛10种石斛属植物中毛兰菲、鼓槌菲、杓兰素等20个菲类活性成分，并介绍其抗肝纤维化、抗肿瘤、抗炎、抗氧化、降血糖等药理活性，希望为该属植物的新药研发和临床应用提供参考。

Phenanthrene compounds are one of the characteristic components of Dendrobium, which can be divided into four types of phenanthrene derivatives such as simple phenanthrene, dihydrophenanthrene, diphenanthrene and phenanthrenequinone (ketone). In this paper, we reviewed 20 phenanthrene components (such as confusarin, chrysotoxene, cypripedin, and so on) in 10 species of Dendrobium, including D. nobile, D. officinale, D. chrysanthum, D. moniliforme, D. fimbriatum, D. densiflorum, D. chrysotoxum, D. gibsonii, D. formosum and D. senile, and introduced their pharmacological activities in anti-liver fibrosis, anti-tumor, antiinflammation, anti-oxidation and hypoglycemic, hoping to provide reference for the subsequent research and development and clinical application of this genus.

R285.5

国家自然科学基金资助项目（82104316）；2022年度南京市中医药科技专项（ZYYB202203）