为了解延胡索近21年的研究热点及临床研究进展，分析其未来研究趋势，分别检索2002年1月1日—2022年12月31日中国学术期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang Data）、中文科技期刊数据库（VIP）、中国生物医学文献数据库（CBM）、PubMed、Web of Science（WOS）数据库中收录的延胡索研究相关的中英文学术期刊，用Endnote X9进行数据整合、去重，用VOS viewer 1.6.18软件进行文献计量和可视化分析。结果显示，延胡索21年来中文文献发表量呈波动上升趋势，英文文献发表量呈平稳上升趋势，总体数量方面中文文献多于英文文献；关键词聚类分析显示延胡索主要研究内容以活性成分与质量研究为主，其次是药对配伍与组方制剂，再次是功效与临床应用。总体而言，延胡索研究方向以药物评价和动物实验居多，而在临床应用与临床试验方面的研究较少，具有完善与深入挖掘的必要性。

In order to understand the research hotspots and clinical research progress of Corydalis Rhizoma in the past 21 years, and analyze its future research trends, the Chinese Academic Journal Full Text Database (CNKI), Wanfang Data Knowledge Service Platform (Wanfang Data), Chinese Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (CBM), Pubmed were searched from January 1, 2002 to December 31, 2022, respectively. And the Chinese and English core academic journals related to Corydalis Rhizoma research included in the Web of Science (WOS) core collection database were integrated and deduplicated using endnote X9, and bibliometric and visual analysis were conducted using VOS viewer 1.6.18 software. The results show that the publication volume of Chinese literature in Corydalis Rhizoma has shown a fluctuating upward trend over the past 21 years, while the publication volume of English literature has shown a steady upward trend. Overall, there are more Chinese literature than English literature. Keyword clustering shows that the main research content of Corydalis Rhizoma currently focuses on the study of active ingredients and quality, followed by drug pair compatibility and formulation, and the third is efficacy and clinical application. Overall, the current research direction of Corydalis Rhizoma is mainly focused on drug evaluation and animal experiments, while there is relatively little research in clinical applications and trials, which is necessary for improvement and exploration. In future research, more consideration should be given to the clinical trial research of Corydalis Rhizoma.

R969.4

国家自然科学基金面上项目（81973895）；北京中医药大学重点攻关项目（2020-JYB-ZDGG-143-3）