万年蒿 Artemisia sacrorum 是中国东北地区的习用药材,有清热解毒、凉血止血、止痛的功效。现代药理学研究表明,万年蒿及其有效成分在保肝、抗癌、抗肿瘤、抗炎、抗肥胖、抗菌、抗氧化、镇痛等方面具有良好的药理活性,同时对万年蒿防治肝损伤、抗癌、抗炎、抗肥胖等的作用机制进行了研究。随着蒿属植物研究的深入,万年蒿作为常用的蒿属植物得到了更多的关注。对万年蒿及其有效成分的药理作用进行综述,以期为进一步利用、质量控制以及新药研发提供依据。

Artemisia sacrorum Ledeb. is a medicine herb used in Northeast China. It has the functions of clearing heat and detoxifying, cooling blood to stop bleeding and relieving pain. Modern pharmacological research shows that A. sacrorum and its active ingredients in hepatoprotective, anti-tumor, anti-inflammatory, anti-obesity, antibacterial, antioxidant, analgesic, etc., and at the same time, the mechanism of action of A. annua in the prevention and treatment of liver damage, anticancer, anti-inflammatory, anti-obesity and so on has been studied. With the development of Artemisia species research, A. sacrorum has received more attention as a commonly used Artemisia species. The pharmacological effects of A. sacrorum and its active ingredients were reviewed in order to provide a basis for further utilization, quality control and new drug development.

R285.5

中医药国际合作专项(基地类项目)(0610-2140NF020630);释药技术与药代动力学国家重点实验室(天津药物研究院)开放课题资助项目(010161003)