[关键词]
[摘要]
芪参益气滴丸是由黄芪、丹参、三七、降香组成的复方制剂,具有补气活血、化瘀的功效。其药理作用主要包括抗炎、抗氧化应激、抑制纤维化、抗凋亡、促血管生成、改善能量代谢、抗血小板等,在冠心病、冠状动脉血运重建术后、高血压合并心脏病、糖尿病合并心脏病等心血管疾病方面有较好的应用前景。从药理作用、临床应用方面研究进展总结芪参益气滴丸的心血管保护特性,以期为该制剂的深度开发及临床合理用药提供理论支持。
[Key word]
[Abstract]
Qiushen Yiqi Dropping Pill (QYDP) is a compound preparation composed of Astragalus membranaceus, Salvia miltiorrhiza, Panax notoginseng, and Dalbergia odorifera, which has the effect of invigorating qi and promoting blood circulation and removing blood stasis. Its pharmacological effects mainly include anti-inflammatory, anti-oxidative stress, inhibition of fibrosis, anti-apoptosis, promotion of angiogenesis, improvement of energy metabolism, anti-platelet, and so on. It has a good application prospect in coronary heart disease, coronary artery revascularization, hypertension with heart disease, diabetes with heart disease, and other cardiovascular diseases. The cardiovascular protective properties of QYDP were summarized from the aspects of pharmacology and clinical application to provide theoretical support for the in-depth development and rational clinical use of this preparation.
[中图分类号]
R287.5
[基金项目]
国家自然科学基金资助项目(81873149);国家科技重大专项重大新药创制项目(2018ZX09734-002)