金花茶Camellia nitidissima为我国广西地区的少数民族常用药，具有清热解毒、利尿消肿等功效。近年来，对于金花茶开展了大量的化学成分和药理学研究，表明金花茶含有黄酮类化合物、多糖、皂苷等多种生物活性成分，该植物及其提取物具有抗肿瘤、抗炎、抗氧化、调血脂、降血糖、抗肥胖、降血压、抗过敏、抗衰老等药理作用。对金花茶化学成分和药理研究进展进行了归纳总结，为更好地利用该植物和新药研发提供理论参考。

Camellia nitidissima is common traditional ethnic medicine in Guangxi, which takes effect by clearing away heat and toxic materials and diuretic detumescence. In recent years, a great number of chemical, and pharmacological studies on Camellia nitidissima Chi have been carried out, primarily in China. Phytochemical investigations have shown that the plant contains a rich source of bioactive constituents, including flavonoids, polysaccharides, saponins, and other components. Pharmacological studies have demonstrated that Camellia nitidissima Chi possesses anti-tumour, anti-inflammatory, antioxidant, hypolipidemic effect, hypoglycemic, anti-obesity, hypotensive, anti-anaphylaxis, and anti-aging properties. The present paper presents an up-to-date overview of the chemical constituents and pharmacological effects of Camellia nitidissima Chi in order to explore the potential of this plant for drug development.

R285.5

国家中医药管理局国际合作司中医药国际合作专项（0610-2140NF020630）；广西创新驱动发展专项资金资助项目（桂科AA18118049-3） ；中国医学科学院医学与健康科技创新工程资助项目（2019-I2M-5-020）