目的 探讨止痛化癥胶囊联合左氧氟沙星治疗慢性盆腔炎的临床疗效。方法 选取2019年9月—2021年2月在泰州市人民医院就诊的106例慢性盆腔炎患者作为研究对象，按照治疗方法将所有患者分为对照组和观察组，各53例。对照组口服左氧氟沙星片，0.1 g/次，3次/d。观察组在对照组基础上口服止痛化癥胶囊，1.2 g/次，3次/d。连续治疗2周。观察两组的临床疗效，比较患者治疗前后的视觉模拟评分法（VAS）评分、炎性包块的最长直径，以及血清中人巨噬细胞趋化蛋白-1（MCP-1）、肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）的水平。结果 治疗后，观察组的总有效率为94.34%，对照组为81.13%，两组比较差异有统计学意义（P<0.05）。治疗后，两组VAS评分均显著降低，盆腔炎性包块的最长直径显著减少（P<0.05）；且观察组显著低于对照组（P<0.05）。治疗后，两组的MCP-1、TNF-α、IL-6水平均显著降低（P<0.05）；治疗后，观察组的MCP-1、TNF-α、IL-6水平显著低于对照组，差异有统计学意义（P<0.05）。结论 止痛化癥胶囊联合左氧氟沙星片治疗慢性盆腔炎的疗效确切，能减轻疼痛程度，缩小炎性包块大小，降低炎症反应，值得临床推广运用。

Objective To investigate the clinical efficacy of Zhitong Huazheng Capsules combined with Levofloxacin Tablets in treatment of chronic pelvic inflammatory disease. Methods A total of 106 patients with chronic pelvic inflammatory disease treated in Taizhou People's Hospital from September 2019 to February 2021 were selected as the research subjects. According to the treatment methods, all patients were divided into control group and observation group, with 53 patients in each group. Patients in the control group were po administered with Levofloxacin Tablets, 0.1 g/time, three times daily. Patients in the observation group were po administered with Zhitong Huazheng Capsules on the basis of control group, 1.2 g/time, three times daily. The treatment lasted for two weeks. The clinical efficacy of the two groups was observed. The visual analogue scale (VAS) score, the longest diameter of inflammatory mass, and the serum levels of MCP-1, TNF-α and IL-6 were compared before and after treatment. Results After treatment, the total effective rate of the observation group was 94.34%, and that of the control group was 81.13%. The difference between the two groups was statistically significant (P < 0.05). After treatment, the VAS score and the longest diameter of pelvic inflammatory mass were significantly decreased in both groups (P < 0.05). And observation group was significantly lower than control group (P < 0.05). After treatment, the levels of MCP-1, TNF-α, and IL-6 in two groups were significantly decreased (P < 0.05). After treatment, the levels of MCP-1, TNF-α, and IL-6 in the observation group were significantly lower than those in the control group, with statistical significance (P < 0.05). Conclusion Zhitong Huazheng Capsules combined with Levofloxacin Tablet has definite efficacy in treatment of chronic pelvic inflammation, which can reduce the degree of pain, reduce the size of inflammatory mass and reduce inflammatory response, and is worthy of clinical promotion and application.

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