[关键词]
[摘要]
金线莲来源于兰科开唇兰属植物金线兰Anoectochilus roxburghii (Wall.)Lindl.,主要分布于中国福建、浙江、江西等地。金线莲多糖作为其主要成分,具有抗糖尿病、保肝、抗炎和抗肿瘤等药理作用,其主要通过抗氧化、调节脂质代谢、调节机体免疫以及诱导细胞凋亡等发挥作用。就金线莲多糖的上述药理作用及作用机制的研究进展进行阐述,旨在为其后续的制剂开发、临床研究与应用提供理论基础及文献依据。
[Key word]
[Abstract]
Anoectochilus roxburghii (Wall.) Lindl. belongs to the orchids, which mainly distributed in Fujian, Zhejiang and Jiangxi provinces. Polysaccharides of Anoectochilus roxburghii is the main component of Anoectochilus roxburghii, which has the effect on the anti-diabetic, hepatoprotective, anti-inflammatory and anti-tumor, mainly through antioxidation, regulation of lipid metabolism, regulation of body immunity and induction of apoptosis. In the review, we summarized the progress of pharmacological action and mechanism of Anoectochilus roxburghii, to provide a theoretical basis and literature for the subsequent preparation development, clinical research and application of the valuable Chinese herb.
[中图分类号]
R285.5
[基金项目]
福州市科技局社会发展项目(2019-SZ-42);福州市感染性疾病医学中心资助项目(2018080306)