目的观察心通口服液治疗冠心病心绞痛患者的临床疗效。方法选取2019年10月-2020年10月内蒙古自治区人民医院治疗的78例冠心病心绞痛患者为研究对象，根据治疗方案将患者分为对照组和观察组，各39例。对照组患者均给予冠心病心绞痛二级预防治疗，观察组在对照组基础上口服心通口服液，10 mL/次，3次/d。两组均治疗4周。比较两组患者的临床疗效、心绞痛的发作次数和持续时间及服用硝酸异山梨酯片的剂量。结果治疗后，观察组总有效率为89.7%，显著高于对照组的69.2%（P<0.05）。治疗后，两组心绞痛发作次数、每次发作持续时间、含服硝酸异山梨酯片剂量均显著降低（P<0.05）；观察组心绞痛发作次数、每次发作持续时间、含服硝酸异山梨酯片剂量显著低于对照组（P<0.05）。结论心通口服液治疗冠心病心绞痛患者可提高治疗有效率，减少心绞痛发作次数、持续时间及硝酸异山梨酯含服剂量，效果优于单纯西药治疗，且相对安全，值得临床应用。

Objective To observe the clinical effect of Xintong Oral Liquid in treatment of coronary heart disease angina pectoris. Methods A total of 78 patients with coronary heart disease and angina pectoris treated in the Inner Mongolia People's Hospital from October 2019 to October 2020 were selected as the research objects. According to the treatment plan, the patients were divided into control group and observation group, with 39 cases in each group. Patients in the control group were given secondary preventive treatment of coronary heart disease and angina pectoris, and observation group was given Xintong Oral Liquid on the basis of control group, 10 mL/time, three times daily. Both groups were treated for 4 weeks. The clinical efficacy, the frequency and duration of angina pectoris attacks and the dosage of isosorbide nitrate tablets were compared between two groups. Results After treatment, the total effective rate of observation group was 89.7%, which was significantly higher than 69.2% of control group (P < 0.05). After treatment, the frequency of angina pectoris attack, the duration of each attack and the dose of isosorbide nitrate tablets were significantly decreased in two groups (P < 0.05). The frequency of angina attack, the duration of each attack and the dose of isosorbide nitrate tablets in the observation group were significantly lower than those in the control group (P < 0.05). Conclusion Xintong Oral Liquid in treatment of patients with coronary heart disease angina pectoris can improve the treatment efficiency, reduce the frequency and duration of angina pectoris attacks, and isosorbide nitrate containing dosage, the effect is better than that of western medicine alone, and is relatively safe, worthy of clinical application.

R972

内蒙古自治区人民医院基金项目（2020YN04）