[关键词]
[摘要]
新型冠状病毒肺炎(COVID-19)患者尤其危重症患者,疾病后常伴有D-二聚体升高,易诱发或者加重缺血性脑卒中的发生。而两种疾病在病史初期均存在头痛、呕吐、发热、呼吸急促等相似症状,容易造成误诊、漏诊,且相互影响,导致病程延长。针对COVID-19患者,需积极尽早采取抗毒病治疗,合并脑卒中的患者,需密切监测D-二聚体的指标变化,根据其指标给予患者适宜的抗栓治疗,一旦D-二聚体升高,建议立即启动抗凝措施,同时需控制患者血压血脂等高危因素。结合脑卒中相关用药研究,探讨COVID-19合并脑卒中这类高危人群的合理用药策略与药学监护,为此类患者提供合理用药参考。
[Key word]
[Abstract]
Coronavirus disease 2019 (COVID-19) patients are particularly critically ill, often accompanied by D-djurogen elevation, easy to induce or aggravate the occurrence of ischemic stroke. Both diseases have similar symptoms such as headache, vomiting, fever and shortness of breath in the early stages of their medical history, which can easily lead to misdiagnosis, missed diagnosis, and mutual influence, resulting in prolonged course of illness. For patients with COVID-19, anti-venom treatment should be actively taken as soon as possible, combined with stroke patients, the indicator change of D-diamer should be closely monitored, according to its indicators to give patients appropriate anti-thrombosis treatment, once the D-diamer rises, it is recommended to start anticoagulant immediately, while controlling the patient's blood pressure lipids and other high-risk factors. In this paper, combined with the research on stroke-related drug use, this paper discusses the rational drug use strategy and pharmacological care of high-risk groups such as COVID-19 combined with stroke, and provides reasonable drug use reference for such patients.
[中图分类号]
[基金项目]
国家重点研发计划项目(2017YFC0909904)