[关键词]
[摘要]
肺炎是一种常见的感染性疾病,其中重症肺炎致病性高、死亡率高。现阶段临床上治疗肺炎的药物相对较多,抗生素类药物的滥用现象也较为严重,给肺炎患者的治疗及预后均带来较大影响。中药以多靶点起效、不良反应低等特点在治疗肺炎方面发挥出越来越重要的作用。注射用丹参多酚酸具有抑制炎症、抗氧化应激、调节免疫和调节肾素-血管紧张素系统(RAS)等作用,通过对该药的药效学及丹参类制剂临床的应用研究进展进行综述,对其治疗肺炎的可行性进行探讨,以期为肺炎的有效治疗提供参考和依据。
[Key word]
[Abstract]
Pneumonia is a common infectious disease, severe pneumonia is characterized by high pathogenicity and high mortality. At the present stage, there are many medicine for treating pneumonia, but the abuse of antibiotics is serious, so it will have a greater impact on the treatment and recovery of pneumonia patients. Traditional Chinese medicine is playing an increasingly important role in the treatment of pneumonia due to its multiple targets and low adverse reactions. According to our previous studies, Salvianolic Acids for Injection (SAFI) has many functions including anti-inflammation, anti-oxidative stress and regulation of immunityand Andrenin-angiotensin System (RAS). In this present study, we summarized the related efficacy and clinical studies of SAFI and salvia miltiorrhiza preparation, as well as the feasibility of its application inthepneumonia patients. So aimed to provide evidence and theoretical guidancefor the application of SAFI in pneumonia patients.
[中图分类号]
R259;R285.6
[基金项目]
天津市科技重大专项与工程“注射用丹参多酚酸临床再评价研究”(18ZXXYSY00120)