[关键词]
[摘要]
目的 观察注射用丹参多酚酸治疗以头晕/眩晕为首发症状急性脑梗死临床疗效。方法 选取齐齐哈尔医学院附属第二医院神经内科2018年6月—2019年6月住院的以头晕/眩晕为首发症状的急性脑梗死病例80例,随机分为观察组和对照组,每组40例。对照组给予抗血小板聚集、他汀稳定血管斑块等常规治疗,观察组在对照组的基础上给予注射用丹参多酚酸,0.13 g加入250 mL 0.9%氯化钠中静滴,1次/d。两组均治疗14 d。观察和比较两组治疗前后的眩晕障碍量表(DHI)评分、日常生活能力评定指数量表(BI)评分。结果 治疗后,两组患者DHI评分显著降低,BI评分显著升高,同组治疗前后比较差异均具有统计学意义(P<0.05);治疗后,与对照组比较,观察组患者BI评分显著升高,DHI评分显著降低,两组比较差异具有统计学意义(P<0.05)。结论 注射用丹参多酚酸在治疗以头晕/眩晕为首发症状的急性脑梗死能够有效提高患者生活能力,改善头晕/眩晕效果更加显著,值得临床推广和应用。
[Key word]
[Abstract]
Objective To observe the clinical efficacy of Salvianolate for injection in treatment of acute cerebral infarction with dizziness/vertigo as the first symptom. Methods Patients (80 cases) with acute cerebral infarction with dizziness/vertigo as the first symptom were enrolled in the department of neurology, the Second Affiliated Hospital of Qiqihar Medical University from June 2018 to June 2019 were randomly divided into observation group and control group, 40 cases in each group. The control group were received anti-platelet aggregation, statins stable vascular plaque, and other conventional treatments. The observation group were iv administered with Salvianolate for injection on the basis of control group, 0.13 g added into 250 mL of 0.9% sodium chloride injection, once daily. Both groups were treated for 14 d. After treatment, the DHI and BI scores in two groups before and after treatment were observed and compared. Results After treatment, DHI scores in two groups were significantly decreased, but the BI scores were increased, and the difference was statistically significant in the same group (P < 0.05). Compare with the control group, BI scores in the observation was significantly increased, DHI was significantly decreased, with significant difference between two groups (P < 0.05). Conclusions Salvianolate for injection in treatment of acute cerebral infarction with dizziness/vertigo as the first symptom can effectively increase the living ability of patients, and improve the effect of dizziness/vertigo is more significant, it is worthy of clinical promotion and application.
[中图分类号]
R969.4
[基金项目]