目的 探讨盆炎净胶囊联合注射用头孢呋辛钠治疗慢性盆腔炎的临床疗效。方法 选择2018年4月—2019年4月在三亚市中医院进行治疗的86例慢性盆腔炎患者为研究对象，根据用药的差别分为观察组（43例）和对照组（43例）。对照组静脉滴注注射用头孢呋辛钠，1.5 g/次，同0.9%氯化钠注射液100 mL配伍，12 h/次；观察组在对照组基础上给予盆炎净胶囊，2.0 g/次，3次/d。两组均治疗2周。观察两组患者的临床疗效，比较两组治疗前后的视觉模拟评分（VAS）、症状积分、世界卫生组织生存质量测定量表（WHOQOL-100）评分及血清学指标。结果 经治疗，对照组有效率为81.40%，显著低于治疗组的95.35%（P<0.05）。经治疗，两组VAS积分、症状积分均下降，WHOQOL-100评分均增高（P<0.05），且观察组上述评分明显优于对照组（P<0.05）。经治疗，两组血清C反应蛋白（CRP）、白细胞介素-1β（IL-1β）、基质金属蛋白酶-2 （MMP-2）、单核细胞趋化蛋白-1（MCP-1）、细胞间黏附分子-1（ICAM-1）、肿瘤坏死因子-α（TNF-α）水平均降低（P<0.05），且观察组血清学指标明显低于对照组（P<0.05）。结论 盆炎净胶囊联合注射用头孢呋辛钠治疗慢性盆腔炎可有效改善患者临床症状，降低机体炎症反应，提高患者生活质量，有着良好临床应用价值。

Objective To explore the clinical efficacy of Penyanjing Capsules combined with Cefuroxime Sodium for injection in treatment of chronic pelvic inflammation. Methods A total of 86 patients with chronic pelvic inflammation who were treated in Sanya Traditional Chinese Medicine Hospital from April 2018 to April 2019 were divided into observation group (43 cases) and control group (43 cases) according to the difference of medication. The control group were iv adminitered with Cefuroxime Sodium for injection, 1.5 g/time, compatible with 0.9% sodium chloride injection 100 mL, once for 12 h. The observation group were given Penyanjing Capsules on the basis of the control group, 2.0 g/time, three times daily. Patients in two groups were treated for 2 weeks. The therapeutic effects were compared, and the VAS, symptom score, WHOQOL-100 score and serological indicators before and after treatment in two groups were compared. Results After treatment, the effective rate of the control group was 81.40%, which was significantly lower than 95.35% of the observation group (P<0.05). After treatment, the VAS score and symptom score in two groups were decreased, but the WHOQOL-100 score were increased (P<0.05). And these scores in the observation group were especially better than those in the control group (P<0.05). After treatment, the levels of CRP, IL-1β, MMP-2, MCP-1, ICAM-1, and TNF-α in two groups were significantly decreased (P<0.05), and the serological indicators in the observation groups were significantly lower than those in the control group (P<0.05). Conclusion Penyanjing Capsules combined with Cefuroxime Sodium for injection in treatment of chronic pelvic inflammation can effectively improve the clinical symptoms of patients, reduce inflammation and improve the quality of life of patients, and has good clinical application value.

R984