[关键词]
[摘要]
全球已上市品种体外检测数据显示,吸入粉雾剂相比气雾剂和吸入溶液肺部沉积率偏低,为药物总量的10%~40%,进入肺部的药物占药物总量的20%~30%,药物利用率较低。旨在讨论通过多种途径提高吸入粉雾剂的有效沉积率,提升药物的治疗效果。
[Key word]
[Abstract]
The in vitro test data of global listed varieties shows that the lung deposition of DPIs is lower than that of pMDI and inhaled solution, which is about 10%-40% of the total amount of drugs, and the drugs that actually enter to the lung account for about 20%-30%. The drug utilization rate is low. The purpose of this paper is to explore various ways to improve the effective deposition of DPIs, so as to improve the therapeutic effect of drugs.
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