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[摘要]
目的 研究注射用丹参多酚酸对急性缺血性脑卒中患者肢体功能及神经功能的影响。方法 选取许昌市中心医院急性缺血性脑卒中患者92例作为研究对象,按随机抽签法分为观察组、对照组,各46例。对照组采取常规治疗,给予抗血小板聚集、降脂稳斑、控制血压、血糖等药物;观察组在对照组基础上采取注射用丹参多酚酸治疗,静脉滴注,0.13 g/次,1次/d,均治疗14 d。比较两组治疗效果;采用简式运动功能量表(FMA)评定治疗前后患者肢体功能;采用美国国立卫生研究院卒中量表(NIHSS)评定神经功能缺损;进行日常生活能力(ADL)评分。结果 观察组总有效率为91.30%,较对照组73.91%显著升高(P<0.05);治疗前,两组FMA、NIHSS、ADL评分无明显差异;治疗14 d后,两组FMA、ADL评分显著升高,NIHSS评分显著降低,与治疗前比较差异显著(P<0.05);观察组FMA、ADL评分较对照组明显升高,NIHSS评分较对照组明显降低,差异有统计学意义(P<0.05),结论 注射用丹参多酚酸应用于急性缺血性脑卒中治疗,治疗效果显著,显著改善患者肢体功能、神经功能,有效提高日常生活能力。
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[Abstract]
Objective To study the effects of salvianolic acid for injection on limb function and neurological function in patients with acute ischemic stroke. Methods A total of 92 patients with acute ischemic stroke in our hospital were enrolled in the study. They were divided into observation group and control group by random sampling method, with 46 cases in each group. The control group received routine treatment, and the observation group was treated with salvia miltiorrhiza polyphenolic acid on the basis of the control group. After 14 days of treatment, the treatment effects, limb function (FMA) score, neurological deficit (NIHSS) score, and daily living ability (ADL) score were compared between the two groups. Results The total effective rate of the observation group was 91.30% (42/46), which was higher than that of the control group (73.91% (34/46)). There was no significant difference in the FMA, NIHSS and ADL scores between the two groups before treatment. After 14 days of treatment, the FMA and ADL scores of the observation group were higher than those of the control group, and the NIHSS score was lower than that of the control group (P<0.05). Conclusion Salvia polyphenolic acid for injection can be used in the treatment of patients with acute ischemic stroke. It can achieve significant therapeutic effects, significantly improve limb function and nerve function, and effectively improve daily living ability. It is worthy of clinical promotion.
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