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[摘要]
目的 观察注射用丹参多酚酸治疗急性脑梗死患者的临床疗效。方法 选择2017年11月-2018年6月在齐齐哈尔医学院附属第三医院进行诊治的急性脑梗死患者64例,随机分为对照组与观察组,各32例。对照组给予常规治疗,观察组在对照组基础上加用注射用丹参多酚酸,每次0.13 g加入250 mL 0.9%氯化钠中静滴,1次/d,疗程均为14 d。根据美国国立卫生研究院卒中量表(NIHSS)判定临床疗效,以改良Rankin量表(mRS)评价神经功能恢复情况。结果 治疗后,对照组与观察组的有效率分别为75%和91%,观察组的治疗有效率明显高于对照组(P<0.05);观察组神经功能恢复明显高于对照组(P<0.05)。结论 注射用丹参多酚酸治疗急性脑梗死患者疗效明显,能促进神经功能改善,无明显副作用,值得临床推广。
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[Abstract]
Objective To investigate the clinical effect of Salvianolic Acids for Injection (SAFI) in the treatment of acute cerebral infarction. Methods A total of 64 patients of acute cerebral infarction in The Third Affiliated Hospital of Qiqihar Medical College from November 2017 to June 2018 were selected and were randomly divided into the observation group and the control group. The patients in the control group received routine medicine therapy, and the patients in the treatment group was received SAFI 0.13 g added for 0.9% sodium chloride 250 mL intravenous drip qd in addition to the treatment of control group. Patients treated once per day and 14 d for one course of treatment, and the prognosis of the two groups were observed by NIHSS scores and mRS scores. Results The treatment efficiency in the observation group and control group respectively were 91% and 75%, and the observation group was significantly higher than that of the control group (P<0.05). The observation group significantly improve neurological function than that of the control group (P<0.05). Conclusion SAFI has good curative effect in the treatment of acute cerebral infarction, which can promote the improvement of neurological function, with no significant side effects, so it is worthy of clinical application.
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