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[摘要]
目的 研究注射用丹参多酚酸治疗急性脑梗死的临床疗效。方法 随机抽取吉林省神经精神病医院2017年3月-2018年7月入院的60例急性脑梗死患者为研究对象,按住院先后顺序编号,以随机选取分组法分为对照组与观察组,每组各30例。对照组采取常规抗血小板聚集、改善微循环等治疗方案,观察组在此基础上加用注射用丹参多酚酸治疗,两组疗程均为2周,比较治疗前后2组美国国立卫生研究院卒中量表(NIHSS)评分、日常生活能力(ADL)评分及蒙特利尔认知评估量表(MoCA)评分,评估治疗效果,统计不良反应。结果 治疗2周后,对照组总有效率为66.7%,观察组总有效率为80.0%,经对比差异有统计学意义(P<0.05)。治疗后两组NIHSS评分明显降低,ADL评分及MoCA评分均明显升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗后观察组NIHSS评分明显低于对照组,ADL评分及MoCA评分均明显高于对照组,差异有统计学意义(P<0.05)。治疗期间2组均未见不良反应发生。结论 注射用丹参多酚酸对急性脑梗死的治疗安全、有效,在临床中值得推广。
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[Abstract]
Objective To study the clinical efficacy of Salvianolic Acids for Injection in treatment of acute cerebral infarction. Method Randomly draw our hospital Sixty patients with acute cerebral infarction who were admitted between 2017-03 and 2018-07 were enrolled in the study. They were numbered according to the order of hospitalization. They were randomly divided into control group and treatment group, with 30 cases in each group. The control group received conventional anti-platelet aggregation and microcirculation to improve the treatment. The treatment group was treated with injection of Salvianolic Acids for Injection. The two groups were treated for 2 weeks. The NIHSS scores of the two groups before and after treatment were compared to evaluate the therapeutic effect. Medical statistics adverse reaction comparison. Results After 2 weeks of treatment, the total effective rate of the control group was 66.7%, and the total effective rate of the treatment group was 80.0%. The difference was statistically significant (P<0.05). After treatment, the NIHSS score of the treatment group decreased to (4.1 ±2.1). There was a difference between the control group and the control group, and the difference was statistically significant (P<0.05). After treatment, the ADL score of the treatment group increased to (73.7 ±10.3) points, which was different from the control group, and the difference was Statistical significance (P<0.05); after treatment, the MoCA score of the treatment group increased to (18.7±4.2) points, compared with the control group, and the difference was statistically significant (P<0.05). No adverse reactions occurred. Conclusion Salvianolic Acids for Injection is safe and effective in the treatment of acute cerebral infarction, and it is worthy of promotion in clinical practice.
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