桂枝茯苓丸是张仲景《金匮要略》的经典名方，由桂枝、茯苓、牡丹皮、白芍、桃仁5味中药组成。近年来的药理和临床研究表明该方应用范围十分广泛，治疗疾病由妇科扩展到男科，常用来治疗痛经、盆腔炎、子宫内膜异位症、子宫肌瘤、卵巢囊肿、乳腺增生、前列腺增生等疾病，其药理作用涉及抗凝、抗炎、抗肿瘤等多个方面。综述其临床及实验研究进展，以期为新药研发提供依据。

Guizhi Fuling Pill is a classical prescription of Zhang Zhongjing's Synopsis of Golden Chamber. It consists of five traditional Chinese medicines:Cinnamomi Ramulus, Poria, Moutan Cortex, Paeoniae Radix Alba, and Persicae Semen. In recent years, pharmacological and clinical researches have shown that the prescription of Guizhi Fuling Pill has wide clinical application, which can be applied for the extended treatment of diseases from gynecology to male. It is often used to treat dysmenorrhea, pelvic inflammation, endometriosis, uterine myoma, ovarian cysts, mammary hyperplasia, prostatic hyperplasia and so on. Its pharmacological mechanism involves anticoagulant, anti-inflammatory, and antitumor. The progress of clinical and experimental research is reviewed in the article in order to provide evidence for new drug research and development.

山东省重点研发计划“中医经方精准化及产业化关键技术示范研究”（2016CYJS08A01）