[关键词]
[摘要]
随着我国人口老龄化进程加速及居民生活方式的转变,冠心病的发病率逐年升高。其中,ST段抬高型心肌梗死(STEMI)是冠心病的严重类型,严重危害人们的生命健康。直接经皮冠状动脉介入治疗(PPCI)是急性心肌梗死患者的首选治疗方式,在国内外已广泛应用。然而,尽管该疗法可有效地开通心外膜大血管恢复血供,但仍有部分患者因发生冠状动脉微循环功能障碍导致远期不良心血管事件的发生。因此预防和治疗冠状动脉微循环功能障碍是诊治急性心肌梗死不可回避且亟待解决的关键科学问题,具有重要的临床应用价值。现就冠状动脉微循环障碍对急性STEMI的影响及其治疗学研究进展做一综述,为STEMI中冠状动脉微循环障碍的诊疗新策略提供理论依据和有益的思路。
[Key word]
[Abstract]
With the acceleration of population aging and the change of the lifestyle of the residents, the incidence of coronary heart disease is rising gradually. ST-segment elevation myocardial infarction is a serious type of coronary heart disease, which seriously endangers people's life. Primary percutaneous coronary intervention is the first choice for acute myocardial infarction and has been effectively opened. The epicardial large vessel, but there are still some patients with coronary microcirculation dysfunction leading to long-term adverse cardiovascular events. Therefore, the prevention and treatment of coronary microcirculation dysfunction is an unavoidable problem in the diagnosis and treatment of acute myocardial infarction. The acute ST-segment of the coronary artery microcirculation disorder is now on the acute segment of the coronary artery. The effect and treatment of elevation myocardial infarction were reviewed to provide evidence for the diagnosis and treatment of coronary microcirculation obstrcation.
[中图分类号]
[基金项目]
江苏大学临床医学科技发展基金(编号JLY20140059)