[关键词]
[摘要]
何首乌因其黑须发、益精髓、延年不老等补益作用在处方及中成药中广泛应用,随着中药现代化的不断进展,关于何首乌及其成分的药理研究也不断深入,何首乌包含蒽醌类、二苯乙烯苷类、酚类、黄酮类、磷脂类等成分,关于何首乌提取物及其主要成分二苯乙烯苷类及蒽醌类药理研究较多;具有抗衰老,降脂保肝、提高免疫力、治疗骨质疏松等作用,通过查阅检索中英文数据库,将何首乌及其主要化学成分药理学作用进行总结归纳,通过查阅古文献记载何首乌传统功效结合现代药理学研究对何首乌及其主要化学成分的药理作用进行探讨,为何首乌的临床应用及进一步开发研究提供思路与依据。
[Key word]
[Abstract]
Polygonum multiflorum is widely used in prescriptions and proprietary Chinese medicines because of its beneficial effects such as black hair, essence of benefit, anti-aging, etc. Polygonum multiflorum contains terpenoids, stilbene glycosides, phenols, flavonoids, phospholipids, etc. Polygonum multiflorum and its main compounds have the effects of Anti-aging, lipid-lowering liver protection, improve immunity, treatment of osteoporosis and other effects. This article summarizes the pharmacological effects of Polygonum multiflorum and its major chemical constituents by consulting the Chinese and English database. By explore the pharmacological effects of Polygonum multiflorum and its main chemical constituents by examining the ancient literature records of the traditional efficacy of Polygonum multiflorum combined with modern pharmacology studies, to provide ideas and basis for the clinical application and further development of Polygonum multiflorum.
[中图分类号]
[基金项目]
重大新药创制专项(2015ZX09501004-003-004)