[关键词]
[摘要]
雷公藤属植物化学成分复杂,具有广泛的药理作用。现在已经从雷公藤属醋酸乙酯提取部位分离得到多种化学成分,主要为二萜类、三萜类、倍半萜类、生物碱类及其他化合物;药理研究表明其具有抗炎、免疫抑制、抗血小板聚集作用和杀虫活性。对雷公藤属醋酸乙酯部位化学成分及药理作用研究进展进行综述,为后续研究提供理论依据。
[Key word]
[Abstract]
The chemical constituents of Tripterygium are complex and have a wide range of pharmacologic effects. A variety of chemical constituents have been isolated from the ethyl acetate extract of Tripterygium. There are mainly diterpenes, triterpenes, sesquiterpenoids, alkaloids and other compounds. Pharmacological studies have shown that it has anti-inflammatory, immunosuppressive, anti-platelet aggregation and insecticidal activity. This review summarizes the research progress of the chemical constituents and pharmacologic effects of ethyl acetate of Tripterygium, and provides a theoretical basis for the future research.
[中图分类号]
[基金项目]
福建省自然科学基金项目(2017J01141,2017J01142);福建省省属公益类科研院所基本科研专项(2015R1031-1);福建省医学创新科研项目(2017-CX-12);福建省中医药科研项目(2017FJZYZY101)