[关键词]
[摘要]
目的 对比分析阿奇霉素与诺氟沙星治疗小儿急性肠胃炎的临床效果。方法 选择2014年1月-2015年1月在成都市龙泉驿区妇幼保健院进行诊治的小儿急性肠胃炎患者100例,随机分为阿奇霉素组与诺氟沙星组,每组各50例。阿奇霉素组静脉注射阿奇霉素治疗,根据患儿体质量每次10 mg/kg,每天1次;诺氟沙星组静脉注射诺氟沙星注射液治疗,每次150 mg,每天2次。比较两组的临床治疗效果,住院时间、呕吐缓解时间、发热缓解时间、腹泻缓解时间以及腹痛缓解时间。结果 阿奇霉素组的有效率为98.00%(49/50),明显高于诺氟沙星组的78.00%(39/50),差异有统计学意义(P<0.05)。阿奇霉素组患儿的住院时间、呕吐缓解时间、发热缓解时间、腹泻缓解时间以及腹痛缓解时间均明显短于诺氟沙星组,差异有统计学意义(P<0.05)。阿奇霉素组的不良反应发生率为4.00%(2/50),与诺氟沙星组的6.00%(3/50)相比无明显差异。结论 阿奇霉素对小儿急性肠胃炎的临床治疗效果明显优于诺氟沙星,安全有效,具有较高的临床应用价值。
[Key word]
[Abstract]
Objective To comparethe clinical efficacy of azithromycin and norfloxacin in treatment of acute gastroenteritis in children.Methods Selected 100 cases of patients with acute gastroenteritis who were treated in our hospital from January 2014 toJanuary 2015, divided into two groups randomly. Azithromycin group was treated with intravenous azithromycin, 450 mg per day, 1 times a day, norfloxacin group was treated with norfloxacin, 400 mg per day, 2 times a day. The clinical effects of two groups were compared, the time of hospitalization, the time of wheezing disappearance, the time of cough disappearance, the normal time of body temperature recovery and the time of pulmonary rale disappearance were recorded.Results After treatment, the effective rate of the azithromycin group was 98.00% (49/50), significantly higher than that of the norfloxacin group 78.00% (39/50) (P< 0.05); the time of hospitalization, the time of wheezing disappearance, the time of cough disappearance, the normal time of body temperature recovery and the disappearance time of lung rale in the azithromycin group were significantly shorter than those in the norfloxacin group (P< 0.05); the adverse reaction rate of the azithromycin group was 4.00% (2/50), has no significant difference with the norfloxacin group 6.00% (3/50).Conclusion Azithromycin is superior to norfloxacin in the treatment of acute gastroenteritis in children, which is safe and effective, and has high clinical value.
[中图分类号]
[基金项目]