目的 对比分析前列地尔注射液与复方丹参注射液治疗糖尿病足的治疗效果。方法 选择2012年1月-2016年12月在北京市昌平区中西医结合医院进行诊治的糖尿病足患者210例，随机分为3组，每组各70例。A组单独采用前列地尔注射液治疗，B组单独采用复方丹参注射液治疗，C组采用前列地尔注射液与复方丹参注射液中西医结合治疗，比较3组的临床治疗效果，治疗前后的血脂水平、尿素氮、肌酐、β2微球蛋白以及尿微量白蛋白水平。结果 C组的有效率为92.86%（65/70），明显高于A组和B组，差异有统计学意义（P<0.05）；治疗后3组的三酰甘油（TG）、总胆固醇（TC）和低密度脂蛋白胆固醇（LDL-C）水平均明显降低，高密度脂蛋白胆固醇（HDL-C）水平均明显升高，同组治疗前后比较差异有统计学意义（P<0.05）；且C组与其他两组比较变化更为明显，差异有统计学意义（P<0.05）。治疗后3组的尿素氮、肌酐、β2微球蛋白以及尿微量白蛋白水平均明显降低，同组治疗前后比较差异有统计学意义（P<0.05）；且C组与其他两组比较降低更为明显，差异有统计学意义（P<0.05）。结论 前列地尔注射液与复方丹参注射液中西医结合治疗对糖尿病足具有显著的临床治疗效果，安全有效，值得应用推广。

Objective To study the therapeutic effects of Alprostadil Injection and Composite Salvia Injection on diabetic foot. Methods Selected 210 cases of patients with diabetic foot who were treated in our hospital from January 2012 to December 2016, divided into three groups randomly. The group A was treated with Alprostadil Injection, group B was treated with Composite Salvia Injection, the group C was treated with Alprostadil Injection and Composite Salvia Injection. The clinical therapeutic effects of the three groups were compared, and the levels of blood lipid, urea nitrogen, creatinine, beta-globulin and urinary microalbumin before and after treatment were compared. Results After treatment, the effective rate of the group C was 92.86% (65/70), significantly higher than that of the group A and B (P < 0.05). After treatment, the levels of TG, TC and LDL-C in the three groups were significantly lower than before treatment (P < 0.05), HDL-C levels were significantly higher than before treatment (P < 0.05), and the group C was more significant (P < 0.05). After treatment, the levels of urea nitrogen, creatinine, beta 2 and urinary microalbumin were significantly decreased in the three groups than before (P < 0.05), and the group C was more significant (P < 0.05). Conclusion The effect of Alprostadil Injection and Composite Salvia Injection on diabetic foot is better, which is safe and effective.